Author: LymphChip

2nd Technology Seminar on the use of Primo

2nd Technology Seminar on the use of Primo

Hélène Delobel from Alvéole presented a technology seminar on the use of Primo for photopatterning applications with many practical examples as published in the literature. Dhanesh Kasi from LUMC shared his experience with Primo further highlighting the advantage of the use of Primo to prototype chip designs and engineer microvascular networks.

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Kick-off Meeting LymphChip

Kick-off Meeting LymphChip

February 15, 2022 The Kick-off Meeting was organized in Spatial Chat in view of COVID-19 restrictions. In total 44 members of LymphChip participated representing the academic partners, co-financing partners and the Advisory Board. Plenary sessions were held to present the aims of LymphChip, to learn about the expectations and contributions from co-financing partners and to evaluate the impact plan, and future plans. In 3 consecutive breakout sessions technical requirements, biological platforms/disease models and the three on-chip-models for heart, intestine and skin/lymph node were discussed....

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Two PhD positions intestine on chip

Wageningen University & Research (WUR) Two PhD positions intestine on chip Click here to respond We are looking for Do you want to study how intestinal stem cells can be used in Organ-on-Chip technology and used in toxicological studies? Do you want to understand how nutrients and chemicals in our food interact with the intestinal epithelium and immune system? Are you motivated to work in an interdisciplinary team of scientists embedded in an ambitions Dutch research consortium? We have two PhD positions that combine intestinal stem cell biology with immunology in Organ-on-Chip...

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Open PhD student position in Si/polymer-based Organs-on-Chip technology

Electronic Components, Technology and Materials (ECTM)Department of Microelectronics, Delft University of Technology Open PhD student position inSi/polymer-based Organs-on-Chip technology Within the LymphChip project funded by NWO, the ECTM group at TU Delft is looking for an enthusiastic and motivated PhD student to investigate and develop innovative sensors and microactuators for Organs-on-Chip devices. OoCs are microfluidic cell culture devices that recapitulate in vivo-like microenvironments to support the expression of properties and functions of human tissues and organs. Such microphysiological...

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hDMT meeting

LymphChip project is presented during the annual hDMT Consortium meeting, November 12th, 2021

On November 12, 2021 Dr Valeria Orlova the project leader of LymphChip will present the LympChip consortium to the members of hDMT. She will highlight the objectives of the three research themes on technology development, on the generation of the hiPSC-derived tissue specific cells and on the integration to ultimately lead to functional organs on chip with integrated vasculature and lymphatics for heart, intestine and skin/lymph nodes.

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PI meeting

LymphChip PI Meeting, October 25th, 2021

On October 25, 2021 the principal investigators of LymphChip gathered online to discuss amongst others the recruitment of PhD students and postdocs (we do have vacancies, please keep an eye on the vacancies page on our website) and the kick-off meeting that is scheduled for February 15, 2022.

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Granting of application:

NWA-ORC grant for Organ-on-Chip models with integrated lymphatics

A 5 million Euro NWA-ORC grant was awarded to hDMT researchers to develop immunocompetent human Organ-on-Chip models with integrated lymph drainage for drug discovery and testing (LymphChip). The project is led by Valeria Orlova (coordinator) from Leiden University Medical Center (LUMC), Christine Mummery (LUMC) and Sue Gibbs (VUMC). The lymphatic system plays a crucial role in our immune system, for example by regulating the immune response to pathogens. Lymphatic dysfunction underlies many diseases and could determine the effectiveness of therapies, whether drug or stem-cell based. Yet,...

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