Paraxial mesoderm as a direct gateway to lymphatic endothelial cells

On the 16th of April, the Leiden Organ-on-Chip Center and Optics11 Life organized a workshop focused on the “Cuore” platform at Mirai House in Leiden. This platform was developed by Optics11 Life and enables contractility measurements of 3D engineered muscle tissues, including cardiac, skeletal and smooth muscle tissue. Optics11 Life talked about the capabilities and potential […]

Following the development of an application note developed in collaboration with the Leiden Organ-on-Chip Center, Fluigent will host a webinar on the topic of flow in Organ-on-Chip models and vascular in vitro modeling. Application note authors Dr. Valeria Orlova and Dr. Dhanesh Kasi from the LUMC will share their insights into vessel-on-chip modelling under dynamic flow conditions, with a […]

Flow conditions and a stable well-defined flow direction are important to culture in vivo-like endothelial cells over time that maintain their organization and function. With help of Dhanesh Khasi, Hanna Lammertse and Valeria Orlova, an application note was put together by Fluigent describing the proper conditions for hiPSCs-derived vascular organ-on-chip model under unidirectional controlled flow: https://www.fluigent.com/resources-support/expertise/application-notes/hipscs-derived-vascular-organ-on-chip