Hélène Delobel from Alvéole presented a technology seminar on the use of Primo for photopatterning applications with many practical examples as published in the literature. Dhanesh Kasi from LUMC shared his experience with Primo further highlighting the advantage of the use of Primo to prototype chip designs and engineer microvascular networks.

We are thrilled with Chiaro Nanoindenter installed in our PRIMO (Alveolé) microfabrication lab at LUMC.  We look forward to exploring the mechanical properties of engineered heart tissues and hydrogels as a part of the LymphChip project.

Vincent Laban, co-founder and CEO of Nostics partner of LymphChip presented a technology seminar on their  Surface Enhanced Raman Spectroscopy technology. This Technology Seminar was the first in a series where the industrial partners of LymphChip present their technology to the members of LymphChip.

Valeria Orlova (LUMC), Sue Gibbs (VUMC) and Carine van Schie (DBF) have been interviewed by NWO about the LymphChip project. For more information please read the full article at:

February 15, 2022 The Kick-off Meeting was organized in Spatial Chat in view of COVID-19 restrictions. In total 44 members of LymphChip participated representing the academic partners, co-financing partners and the Advisory Board. Plenary sessions were held to present the aims of LymphChip, to learn about the expectations and contributions from co-financing partners and to evaluate the impact plan, and future plans. In 3 consecutive breakout sessions technical requirements, biological platforms/disease models and the three on-chip-models for heart, intestine and skin/lymph node were discussed....

On November 12, 2021 Dr Valeria Orlova the project leader of LymphChip will present the LympChip consortium to the members of hDMT. She will highlight the objectives of the three research themes on technology development, on the generation of the hiPSC-derived tissue specific cells and on the integration to ultimately lead to functional organs on chip with integrated vasculature and lymphatics for heart, intestine and skin/lymph nodes.

On October 25, 2021 the principal investigators of LymphChip gathered online to discuss amongst others the recruitment of PhD students and postdocs (we do have vacancies, please keep an eye on the vacancies page on our website) and the kick-off meeting that is scheduled for February 15, 2022.

A 5 million Euro NWA-ORC grant was awarded to hDMT researchers to develop immunocompetent human Organ-on-Chip models with integrated lymph drainage for drug discovery and testing (LymphChip). The project is led by Valeria Orlova (coordinator) from Leiden University Medical Center (LUMC), Christine Mummery (LUMC) and Sue Gibbs (VUMC). The lymphatic system plays a crucial role in our immune system, for example by regulating the immune response to pathogens. Lymphatic dysfunction underlies many diseases and could determine the effectiveness of therapies, whether drug or stem-cell based. Yet,...